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Formulations above 100mg/mL can cause localized irritation due to osmotic shifts in surrounding tissue

An RCT in 72 patients with NAFLD found that NAC (600 mg twice daily) for 3 months significantly improved liver enzymes (ALT, AST) and markers of oxidative stress compared to control, though it did not significantly improve liver histology on biopsy (Khoshbaten et al., Hepat Mon, 2010) [33]

In other words, foods high in lycopene havent been shown to lower IGF-1 levels, but they may have other health benefits

Systemic Effects: While particularly effective at local injury sites, the stack also supports systemic health, improving overall resilience and wellness

doi:10.1101/cshperspect.a040576

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