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Abstract Obesity is accompanied with accumulation and pro-inflammatory polarization of macrophages in adipose tissue (AT), leading to systematical inflammation and insulin resistance

He suggested bumping my metformin from two tablets a day to three (I can eventually go up to four, but were doing it gradually to monitor for any new side effects)

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The apparent lack of a direct effect was noted due to the in vitro environment not mimicking the inherent environment of a tendon in vivo

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Brown adipose tissue plays a protective role under stress conditions such as ischemia and hypoxia (166)