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While tesamorelin requires a consistent daily regimen, sermorelin protocols may vary, with some users following a 5-day-on, 2-day-off schedule to optimize GH stimulation

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However, both interventions can influence metabolic processes, glucose homeostasis, and energy balance, which warrants careful consideration

A small subset (10-20%) can discontinue successfully if they've built strong lifestyle habits, but this requires careful medical planning

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