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Epidemiologist and public health specialist from the University of Melbournes School of Population and Global Health, Professor Tony Blakely, says the US study adds to the growing knowledge of the wide-ranging effects of GLP-1RAs

Still, the findings follow previous research that linked the drugs to a higher risk of osteoporosis-related fractures in older adults with Type 2 diabetes and reduced bone density

Retatrutide uses a triple receptor mechanism (GIP, GLP-1, and glucagon) while Mounjaro targets only two receptors (GIP and GLP-1)

Individual factors such as metabolic rate, hormonal adaptation, and dietary habits can also reduce the medication's appetite-suppressing effect

Proper nutrition and staying hydrated help minimize potential side effects

and retatrutide, 24.1 5.8%) (Fig