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Clinical translation requires human CSF pharmacokinetic assays to prove BBB bypass, a rigorous dose-escalation Phase I trial to establish a safe human NOAEL for chronic dosing, and an RCT utilizing precise neurocognitive testing (e.g., MoCA) to confirm that murine transcriptomic shifts yield functional neuroprotection in humans

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Notably, G/D-CuP exerted anti-inflammatory and antioxidative properties, promoting angiogenesis, fibroblast proliferation, and migration to accelerate wound healing without the need for additional bioactive substances