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Spinocerebellar ataxia type 2 Spinocerebellar ataxia type 2a genetic neurodegenerative disorder due to a CAG repeat expansion mutation in the ATXN2 gene coding for the protein ataxin-2 63 has been associated to oxidative stress, in particular due to alterations in the enzymatic activity of antioxidant enzymes including GSTs 64
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High-resolution mass spectrometry instruments utilizing Orbitrap or Time-of-Flight (TOF) technologies provide the mass accuracy essential for confident lipid identification
Blood GSH/GSSG ratio compared to unprotected glutathione
Preliminary evaluation of the antiglycoxidant activity of verapamil using various in vitro and in Silico biochemical/biophysical methods
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