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Given that it has two different mechanisms of action, it appears to have a more significant effect on weight and blood sugar than GLP-1 agonist drugs alone, such as semaglutide or liraglutide, which are both currently FDA-approved for sugar and weight control under different trade names
However, the medication is contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2
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Consequently, the accumulated NAPQI binds covalently to the cysteine, methionine, tyrosine, and tryptophan residues of various proteins, forming NAPQI-protein adducts within the cell that disrupt normal physiological protein functions
These ampoules are intended for intramuscular injection only.