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For patients who find self-injection challenging or who value the simplicity of a pen device, brand-name may be preferred

Meanwhile, new competitive threats continued to surface: in 2025, Lilly unveiled impressive results for an oral GLP-1 pill (orforglipron) that in trials matched injectable Ozempic's efficacy, news that instantly added ~$100 billion to Lilly's market cap

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Continuous glucose monitoring versus usual care in patients with type 2 diabetes receiving multiple daily insulin injections: a randomized trial

Potential Medical Treatments and Interventions If strict adherence to postural and volume administration protocols fails to resolve the agonizing daily throat tightness, medical intervention is mandated to protect the esophageal tissue