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Antimicrobial peptides, on the other hand, play a crucial role in the immune system, protecting the body against infections and diseases

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As a research reagent it is used to probe type 1 IGF receptor activation, downstream PI3K and MAPK signalling, IGF binding protein biology, and the specific question of how much native IGF-I behaviour reflects IGFBP sequestration rather than receptor pharmacology

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The brief report is the first study of its kind, the researchers say, to establish a link between the use of such drugs, called GLP-1 agonists, for weight loss and the risk of such gastrointestinal conditions

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Agents already in routine practicebevacizumab, trastuzumab and mirvetuximab soravtansineprovide compelling clinical precedents, while pipeline ADCs and recombinant modulators promise an expanding repertoire of ovary-sparing therapeutics

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Application of quantitative motor assessments in Friedreich ataxia and evaluation of their relation to clinical measures

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GLP-1 drugs still show promise for addressing mid- and late-life modifiable risk factors to prevent or delay the onset of Alzheimers disease

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