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This VEGF upregulation was diminished when L-carnitine production was inhibited by Mildronate, consistent with in vivo observations (Fig

Therefore, the low rate of patients reaching a complete proteinuria response in clinical trials might not necessarily indicate insufficient control of SLE activity but rather reflect a lacking appreciation and therapy of kidney damage accrual, and, more specifically, of CKD 12

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we await final post-mortem confirmation

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