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The more common symptoms include: Abdominal pain Diarrhea Nausea Vomiting Indigestion Constipation Bloating Headaches In some rare cases, GLP-1 agonists can cause the following: Pancreatitis Hypersensitivity reaction Hypoglycemia Thyroid problems Renal problems Mood swings Gallbladder problems Changes in eyesight Why Choose Cosmetic Injectables Center Medspa for GLP-1 Agonist GLP1 agonist therapy at Cosmetic Injectables Center Medspa is delivered within a physician-led medical spa in Sherman Oaks, where medication selection, dose escalation, and cardiometabolic risk factors are managed as part of structured medical care

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Martins et al

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The dosing schedule of retatrutide is as follows: Weeks 1-4: 1 mg or 2 mg once weekly (starting dose) Weeks 5-8: 4 mg once weekly Weeks 9-12: 8 mg once weekly Week 13+: 8 mg or 12 mg once weekly (Maintenance Dose) However, some trial arms tested higher doses (up to 8 mg or 12 mg as the final dose)

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Moreover, they are resistant to DPP-4 activity and have a longer half-life than native GLP-1

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