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LDHA: lactate dehydrogenase A

Regulating TAM iron metabolism within the TIME, specifically by promoting iron uptake and storage in M2-type macrophages while inhibiting iron release, allows iron accumulation in TAMs to enhance ROS production, increase p300/CBP acetyltransferase activity, and promote p53 acetylation

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Fast and efficient phase II metabolism keeps toxic metabolites moving out of the body quickly

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