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However, as prescription of semaglutide and similar medications escalated, anecdotal reports of reduced alcohol use became very common, and suggested the potential of these more potent therapies for treatment of alcohol use disorder. While the findings are promising, the researchers still need to determine exactly how semaglutide reduces alcohol cravings

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Both participants and study staff were blinded to treatment assignment

doi: 10.1056/NEJMoa2206038 104 GarveyWTFriasJPJastreboffAMLe RouxCWSattarNAizenbergDet al