One patient lost 2.9 kg
Women have much higher prevalence of severe obesity than men [2], and are typically more likely to engage with health (and preventive) services [43], engage with weight management services, and discuss weight loss with healthcare professionals [24], which may facilitate greater access to emerging treatments like GLP-1 and GLP-1/GIP medications
Most peptide doses fall between 5 and 50 units, so either size works
Variation in GLP-1 receptor expression, hepatic metabolism, insulin sensitivity, and gut microbiota composition all influence therapeutic response
Buchwald H, Avidor Y, Braunwald E, et al
Both are highly effective GLP-1 medications, but Tirzepatide has a dual mechanismit activates both GLP-1 and GIP receptors, which may lead to greater weight loss (up to 22% vs 15-17%)