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Types, natural sources and mechanism of action of antioxidants An AOX is a natural substance that provides protection to the living cell against oxidative damage and deleterious effects of ROS ( Enzymatic AOXs include glutathione (GSH) peroxidase, glutathione reductase, catalase (CAT) and superoxide dismutase (SOD) ( Table 1 summarizes the types, natural dietary sources and the mechanism(s) of action of AOXs

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Toxicity and Safety While oral glutathione and inhaled glutathione have limitations due to systemic availability, IV therapy offers a safer and more effective alternative under clinical supervision

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These therapies have a narrow therapeutic window, indicating that their efficacy and toxicity are critically dose dependent

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