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After esophagectomy, CRP levels typically peak on postoperative day 23 and then gradually decline

PMID: 12 ZabottiADe MarcoGGossecLBaraliakosXAletahaDIagnoccoAet al

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Fatigue accompanied by anhedonia, sleep disturbances, or changes in appetite beyond those expected from the medication warrants evaluation for depression, potentially using validated screening tools like the PHQ-9

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PLoS ONE 16 , e0251595 (2021)