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446 OT is mainly produced by neurons located in the paraventricular nucleus (PVN) and supraventricular nucleus (SON) of the hypothalamicneurohypophysial system

Since GLP-1 acts on multiple pathways that are not fully addressed by other therapies, GLP-1 receptor agonists (drugs that mimic GLP-1 to improve insulin response and reduce glucose levels) have become the foundation for medications used in modern diabetes management 3

This finding could lead to new guidelines to treat T1D in adults if replicated in a randomized trial

T., Killeen, A

Kundert, A