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Cancer 123 , 19501955 (2008)

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Efficacy of tirzepatide versus SGLT2 inhibitors in metabolic dysfunction-associated steatotic liver disease (MASLD): a multicenter propensity-matched real-world study In this large real-world analysis using the TriNetX US Collaborative Network, we compared 43,743 tirzepatide initiators vs 43,743 propensity score-matched SGLT2 inhibitor users with MASLD and metabolic comorbidities

Markey KA, Ottridge R, Mitchell JL et al (2017) Assessing the Efficacy and Safety of an 11beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor (AZD4017) in the Idiopathic Intracranial Hypertension Drug Trial, IIH:DT: Clinical Methods and Design for a Phase II Randomized Controlled Trial

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But this synergy depends entirely on receptor availability and circadian priming