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Indeed, evidence indicates that VMAT2 is the only monoaminergic neurotransmitter expressed in CNS neurons

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Oxidative stress can activate multiple stress-sensitive pathways, including the nuclear transcription factor-B (NF-B), p38 mitogen-activated protein kinase (p38MAPK) and c-Jun amino-terminal kinase/stress-activated protein kinase (JNK/SAPK) pathways, impairing insulin signaling processes (Newsholme et al., 2007)

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A phase 1 study of prasugrel in patients with sickle cell disease: effects on biomarkers of platelet activation and coagulation

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