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14,15,16 In addition to oxidative stress, there is a disruption of glutamate homeostasis during opioid withdrawal resulting in an increase in synaptic glutamate (excitatory neurotransmitter) that leads to increased neuronal firing
Trindade, M
Archived from the original on 10 September 2017
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The mechanism involves the formation of complexes with the cell wall of bacteria by surface-exposed polypeptides or cell membrane enzymes and adhesion, which blocks ion channels and inhibits electron flow in the electron transport chain which determines adenosine triphosphates (ATP) production by electron scavenging and also the disruption of cell wall integrity (100)
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