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Patients with Leber's disease, a rare hereditary condition that causes optic nerve deterioration, should inform their doctor before using the nasal spray

To inject Intra muscularly (I.M.) I use a 2ml syringe , although the ampoule is 1ml This ensures that I get every last drop of precious B12 into the syringe .I use a long 1 1/2 inch needle to extract the B12 from the ampoule

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Blood, 112 (6), 22142221

(National Institute of Health or NIH Vitamin B12 shots are normally available by prescription only, although dosage varies depending on age and medical history

For most people, it starts with the typical anemia symptoms - fatigue, pale skin, shortness of breath, etc, and progresses to more neurological symptoms as the condition worsens