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Dose optimization depends on specific research objectives, administration route, and whether acute effects or long-term structural changes are being measured

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(2009) found that a higher amount of Hcy in follicular fluid of PCOS women undergoing oocyte pick-up following FSH stimulation sharply marked lower oocyte quality, fertilization rates, embryo quality, and pregnancy rates with no pregnancies occurring in women whose sampled follicles contained more than 8 molar Hcy [13]

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Once the study concluded, pQCT scans were performed on the femurs to gather additional data

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