A new Cleveland Clinic analysis of nearly 8,000 patients suggests that discontinuing semaglutide and tirzepatide, on average, does not lead to significant weight regain in clinical practice, as many patients later restart the original medication or try an alternative obesity treatment
If constipation becomes a problem despite preparation, options worth discussing with your clinician include: A gentle osmotic laxative such as polyethylene glycol (MiraLAX) used on a scheduled rather than as-needed basis during dose escalation periods
The mechanisms of GLP-1 RAs action in retinopathy and NAION remain incompletely understood, highlighting the need for large trials with baseline retinal grading and extended follow-up
These medications are highly effective, often leading to significant health improvements with minimal side effects
Table of Contents: How do GLP-1 medications support weight loss
They slow how quickly food moves from your stomach into your intestines