Body aches are not a common primary side effect of GLP-1 medications, yet some patients report musculoskeletal discomfort during treatment initiation or dose escalation
A previous study revealed that gastric emptying delay is a physiological effect that attenuates with ongoing treatment, with evidence suggesting that after more than 12 weeks of continuous GLP-1 RA therapy, standard fasting times are likely to be sufficient for most low-risk patients [3]
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Highlights: GLP-1 synthesis, metabolism, and the expression of the receptor show diversity across tissues