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Self-prescribing unlicensed peptides carries real and potentially serious health risks
NaseribafroueiAHestadKAvershinaESekeljaMLinlkkenAWilsonRet al
Regulatory concerns : As with any medication, there are regulatory and approval processes that govern its use, which can affect accessibility
Even though they are FDA approved, cost remains prohibitive for many patients. If the pill costs a lot less out-of-pocket than injected GLP-1 drugs, this may lead more people to choose it even though it may not produce as much weight loss, says Clifford Rosen, MD, a professor at Tufts University School of Medicine and the associate director of the MaineHealth Institute for Research in Scarborough
303 Interestingly, intracerebroventricular administration of GLP-1 did not inhibit feeding in GLP-1R knockout mice but did in wild-type mice, suggesting that GLP-1R signalling mediates satiety, although no evidence for abnormal body weight or feeding behaviour was reported in GLP-1R knockout mice
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