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Molecular mechanisms of ferroptosis and its role in cancer therapy

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Ferrere et al

Pathology of Melanocytic Nevi and Malignant Melanoma

Regulatory cell death modalities include classical apoptosis, necroptosis, pyroptosis and ferroptosis, with ferroptosis as a novel regulatory cell death driven by iron-dependent lipid peroxidation, is regulated by intracellular iron metabolism, lipid metabolism, the GSH/GPX4 repair system, coenzyme Q10, and other genes 26,27,28,29