What the Research Shows: BPC-157 and Knee Structures All BPC-157 research on knee-specific structures comes from animal models, with one exception
The growth-promoting effects of growth hormone include muscle tissue hypertrophy (which may be desired by some but represents an anabolic effect), bone growth and remodeling (problematic after growth plates close), organ enlargement with chronic supraphysiologic doses (cardiac hypertrophy, acromegaly features), connective tissue proliferation (potentially contributing to joint pain and carpal tunnel syndrome), and cellular proliferation that may support tumor growth in susceptible individuals
NNMT is present primarily in the liver, but also in other tissues such as adipose tissue, kidneys, brain, lungs, heart, and muscle
If your medication is prohibited, then you might need to apply for a Therapeutic Use Exemption
He R, Wang B, Cui M, Xiong Z, Lin H, Zhao L, et al
Twice-daily dosing (500mcg morning and evening) shows up in more aggressive protocols but adds cost and injection logistics on top of an already-active TRT schedule