More specifically, this may be observed with respect to certain genes, including Egr, Nos, Srf, Vegr, Akt1, Plc , and Kras genes (Vukojevic et al., 2018), all of which are responsible for the synthesis of factors necessary for a diverse set of processes
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The same reaction can occur on protein cysteine, and the formed GSNO group functions as important intermediate in NO metabolism, a critical player in fulfilling the biolgogical function of NO in signal transduction (Chung, 2006)
[3] It is important to keep in mind that these drugs are relatively new and the impact and long-term side effects may still be largely unknown
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However, this delayed process can cause temporary side effects like nausea, bloating, and constipation, especially during dose escalation