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Mierzejewska, P
This is not the case for over-the-counter remedies for menopausal symptoms.The AMS advocates that all therapies, whether prescription or alternative, should not be used unless there is good research evidence for their effectiveness and safety over the short and long term.CM&T use in AustraliaIn a national representative sample of 10,011 Australian women aged 59-64 years:539% of menopausal women consulted CM&T practitioners.75% used self-prescribed CM&T.95% consulted general practitioners (GP) and 50% consulted specialists during the previous year, and 12% were current menopausal hormone therapy (MHT) users.Similarly, a cross-sectional questionnaire-based study of 2020 Australian women aged 40-65 years living independently in the community found that the prevalence of CM&T use to manage menopausal vasomotor symptoms (VMS) was 13.22%.6Specific herbal and botanical therapiesBlack cohosh (Cimicifuga racemosa or Actaea racemosa)Specific extracts of black cohosh (isopropanolic), and higher therapeutic doses may improve menopausal symptoms, including hot flushes, as shown in a recent systematic review and meta-analysis.7 It should be noted that most of the included studies were conducted over short time frames (i.e
As a result of Novo Nordisks marketing, Ozempic prescriptions reached an all-time high of 373,000 in one week in February of 2023, more than half of which were new prescriptions
The most significant concern is additive blood pressure lowering , which could occur when retatrutide is used alongside agents such as: ACE inhibitors or angiotensin receptor blockers (ARBs) commonly prescribed in obesity-related hypertension and diabetic nephropathy Calcium channel blockers which may compound vasodilatory effects Thiazide or loop diuretics where volume depletion may be exacerbated by any natriuretic effects of GLP-1 receptor activation and by gastrointestinal fluid losses Alpha-blockers associated with a higher baseline risk of postural (orthostatic) hypotension Beta-blockers relevant given the modest heart rate increase associated with GLP-1 receptor agonists
