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However, Ca 2+ -channel blockers have failed to become an established treatment for bipolar disorder as there is mixed evidence on their efficacy, which perhaps argues that the observed increase in free intracellular Ca 2+ in patients may simply be a marker of the underlying disturbance rather than causative [25]

Oxford English Dictionary

This unpredictability can be particularly challenging if you're trying to conceive

There were at least three randomized, double-blind, placebo-controlled trials conducted on adults using Wegovy who were either obese or overweight

"Malignant peripheral nerve sheath tumours in neurofibromatosis 1"

Bipolar disorder as a mitochondrial disease