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These antibodies are used to treat a variety of solid and blood tumors and include anti-CTLA-4 antibodies (ipilimumab), anti-PD-1 antibodies (nivolumab, pembrolizumab), and anti-PD-L1 antibodies (atezolizumab, durvalumab, avelumab)

b , Close-up view in this map shows density connecting helix 8 and G at the position of R419 of helix 8 and G310H311 of G

doi:10.1080/14712598.2019.1581761

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Structural and mechanistic insights into the Keap1-Nrf2 system as a route to drug discovery