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On this basis, we conclude that metformin should not be seen as a quick fix panacea for aging at the expense of non-pharmacologic interventions such as diet, exercise, and related lifestyle changes

Both Semaglutide GLP-1 and Zepbound are intended for long-term usage in medical weight management

For example, conditions such as thyroid disorders , polycystic ovary syndrome (PCOS) , and insulin resistance can affect how well these medications manage appetite and metabolism

This can significantly reduce the risk of developing or worsening weight-related conditions like type 2 diabetes, heart disease, and stroke

We estimated both crude and adjusted HRs for primary and secondary outcomes