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Studies in rodents suggest that a reduction in leptin level during weight loss signals to the brain to increase feeding and decrease energy expenditure

Will the beta cells continue to produce insulin or will insulin production decline as it does typically with T1D

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Additionally, GLP-1 receptors in the hypothalamus interact with key appetite-regulating neuropeptides, including pro-opiomelanocortin (POMC) and neuropeptide Y (NPY)