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Xu F, Yu S, Qin M, Mao Y, Jin L, Che N, et al

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The SURMOUNT-1 trial (tirzepatide, published in NEJM 2022) demonstrated that participants with obesity or overweight without diabetes who received tirzepatide experienced weight reductions of 16.0% (5mg), 21.4% (10mg), and 22.5% (15mg) over 72 weeks

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Without adequate NAD levels, cells cannot efficiently generate ATP, the primary energy currency of the body