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Selenium deficiency may decrease the acetaminophen dose necessary to produce toxicity, and coadministration with NAC may be more effective than NAC alone

Present at millimolar concentrations in most mammalian cells, GSH is involved in virtually every aspect of cellular defence and metabolic regulation

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doi: 10.1002/art.21375 68 BeinerELucasVReichertJBuhaiDVJesinghausMVockSet al

279, 4272642731.10.1074/jbc.M405127200 25 JezJ