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[DOI] [Google Scholar] 170.Meric-Bernstam F., Lee R.J., Carthon B.C., Iliopoulos O., Mier J.W., Patel M.R., Tannir N.M., Owonikoko T.K., Haas N.B., Voss M.H., et al

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A new series of vitamin D analogs is highly active for clonal inhibition, differentiation, and induction of WAF1 in myeloid leukemia

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10.1124/dmd.32.7.752 195 ZhangY.ZhangL.ZhangY.XuJ

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Mechanistically, CB-839 elevates the levels of intracellular ROS, enhances the movement of Nrf2 into the nucleus, leading to an increase in uridine phosphorylase 1 (UPP1) mRNA expression

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some research suggests it stays in circulation longer

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