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Reinscheid et al., 1995), each generating biologically active peptides that are released at the synaptic terminals of opioidergic neurons
Pharmacological effects of AVE 0991, a nonpeptide angiotensin-(1-7) receptor agonist
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Systemic effects that have been reported in trials, or that are mechanistically expected from elevated GH and IGF-1, include: Water retention and mild edema , particularly in the hands, ankles, and face Tingling, numbness, or 'pins and needles' (paresthesia) , sometimes linked to fluid pressure on nerves Headache and facial flushing , often shortly after administration Joint aches or stiffness (arthralgia) Transient changes in blood glucose due to GH's counter-regulatory effect on insulin Fatigue, dizziness, or a feeling of light-headedness in some individuals It is important to be candid about the limits of this evidence
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Glucagon-like peptide-1, a new hormone of the entero-insular axis
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