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Initially developed for type 2 diabetes management, GLP-1 agonists effectively promote weight loss in preclinical and clinical studies [11] [12], leading to their investigation and subsequent approval for obesity treatment in non-diabetic patients

Originally designed to treat type 2 diabetes, some are now FDA-approved for weight management (Wegovy and Zepbound ), and others can be prescribed off-label for weight loss (Ozempic and Mounjaro )

Typically, you will see CJC-1295 compounded with Ipamorelin due to its ability to stimulate GHRH for enhanced results

When combined with GLP-1 and GIP (which manage insulin and appetite), the net result is an increased metabolic rate without problematic blood sugar spikes

PubMed PMID 40789979, 2025