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Elevated ApoB, subclinical thyroid dysfunction, and insulin resistance were frequently cited discoveries

All safety data comes from animal models (primarily rats and mice)

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Systemic toxicity-collectively termed local anesthetic systemic toxicity (LAST)-necessitates prompt airway control, seizure suppression with benzodiazepines, and lipid emulsion therapy, which sequesters lipophilic drug molecules and improves hemodynamic stability