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This increase is likely to continue due to their significant benefits in weight management and cardiorenal protection observed in individuals with type 2 diabetes and the general obese population, Shao said, noting that urgent studies are needed to better elucidate the benefits and risks of the GLP-1 and SGLT2 drug classes in T1D

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the clinical outcome evidence is preliminary

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GLP-1 receptor activation also increases glucose-dependent insulin secretion, suppresses glucagon secretion, slows gastric emptying, and promotes satiety through central nervous system pathways

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