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As most of the available evidence stems from in vitro and preclinical studies, there remains a need for long-term and in vivo research to substantiate these findings and assess their translational relevance

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A 2026 Journal of Marketing Research study found that US households with at least one GLP-1 user reduced grocery spending by 5.3% within six months of adoption

Because MPNSTs may grow aggressively, local invasion into surrounding tissues such as bone, muscle, or organs can lead to secondary symptoms like swelling, restricted range of motion, or systemic signs such as fatigue or unintended weight loss, especially in advanced cases