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254,255 High-fat diet-fed mice treated with exendin-4 (a hormone found in the saliva of the Gila monster which is synthetically modified to produce exenatide for T2D treatment) had decreased mRNA levels of the pro-inflammatory cytokines tumour necrosis factor-alpha, monocyte chemoattractant protein 1 and signal transducer and activator of transcription 3

Therefore, a novel approach to combat metabolic disorders is needed

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Toujeo pricing Toujeo, as a mature insulin product, has relatively established pricing, though insulin costs in the United States remain controversial

Retrieved 13 August 2009