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The GLP-1 space is moving fast

Participants were randomly assigned to semaglutide 2.4 mg once weekly (n=35) or placebo (n=35), alongside lifestyle intervention incorporating a 500 kcal daily energy deficit and increased physical activity

If this translates to humans, BRP could make sustained weight loss treatment accessible to patients who cannot tolerate current options

In studies, participants receiving higher retatrutide doses achieved average weight reductions approaching or exceeding 24% of their starting body weight

Microdosing does not necessarily prevent side effects

Sunada N, Takekita Y, Nonen S, Wakeno M, Koshikawa Y, Ogata H, et al