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If your symptoms are severe, persistent, or accompanied by other symptoms like belly pain, contact your healthcare provider

Written by: Chris Butt, Certified Personal Trainer & Weight Loss Coach, Premier Fitness Camp | Last updated: July 13, 2026 Most people notice strength gains within 48 weeks of consistent resistance training after GLP-1 use

The point is to get you to your personal goal while keeping you safe and healthy.

In the SUSTAIN-6 trial, semaglutide was associated with a significant increased risk of diabetic retinopathy complications, including vitreous hemorrhage, blindness, or conditions requiring treatment with an intravitreal agent or photocoagulation (HR 1.76, 95% CI 1.112.78) [27]

For Zepbound, the once-weekly starting dosage is 2.5 mg for 4 weeks