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4.6 Anti-inflammatory effects in asthma and allergic diseases Asthma and allergic diseases are characterized by chronic inflammation and atypical immune responses, mediated through complex interactions among multiple immune cells, with both innate and adaptive immunity being essential

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Whereas the levels of 1,2-benzoquinone, 11-dehydro-thromboxane B2, 12-KETE, L-malic acid, N2-succinyl-L-ornithine, ornithine, argininosuccinic acid from the fecal metabolites gradually decreased as CKD progressed, chlorohydroquinone, hydroquinone, L-cystine, fecal 12-keto-tetrahydro-leukotriene B4 (12-keto-tetrahydro-LTB4), and L-cysteine levels gradually increased Integrated network analysis based on metabolomics and metagenomics data revealed that Ruminococcus bromii , fecal hydroquinone, and serum creatinine were the major contributors to this network, therefore play major roles in CKD progression

[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Boone DL, Dassopoulos T, Lodolce JP, Chai S, Chien M, Ma A

However, the dual role of MMPs in both injury and tissue repair underscores the importance of temporal precision

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