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Lets take a look at some of the options: Tirzepatide Tirzepatide works similarly to semaglutide but targets a second receptor in addition to the GLP-1 receptors

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doi:10.1016/S0040-4039(01)83796-5 Escher BI, Bramaz N, Richter M, Lienert J (2006) Comparative ecotoxicological hazard assessment of beta-blockers and their human metabolites using a mode-of-action-based test battery and a QSAR approach