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In cases where hyperpigmentation occurs, there are several effective treatments and management strategies: 1

S100a8 silencing attenuates inflammation, oxidative stress and apoptosis in BV2 cells induced by oxygen-glucose deprivation and reoxygenation by upregulating GAB1 expression

8 Your body uses vitamin C to keep glutathione working effectively

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Supplementation of the culture medium with LC during the in vitro maturation of the oocytes favored the acquisition of competence for development, as it improved cytoplasmic and nuclear maturation and reduced ROS levels in the culture medium, showing an antioxidant effect [102]

The remaining 3 studies, scored eight and nine, indicating high-quality studies with low risk of bias (Table 5)