I doubt I'd be sueing myself, eh
doi: 10.3389/fphys.2020.00061 138 KapoorG.SaigalS.ElongavanA
Perez-Leighton, Butterick-Peterson, Billington, and Kotz (2013) proposed that throughout development of obesity, there are changes in orexinergic signaling, perhaps reducing orexinergic signaling gain by changes in synaptic plasticity, which continue to change orexin system responsiveness and promote further development of obesity
Australian family physician
Although still reversible, Grade 2 requires more rigorous lifestyle interventions, including a balanced diet low in processed sugars and saturated fats, and possibly medical treatment to address associated conditions like insulin resistance or high cholesterol
J Cell Physiol 1999