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Triggers of elevated ceramide levels comprise hyperosmotic shock [122], secreted sphingomyelinases (SMases) during inflammation [125], sepsis [126] or severe coronavirus disease 2019 (COVID-19) [127], Clostridium perfringens epsilon toxin [128], and platelet-activating factor [129]

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Until larger, well-designed clinical trials are completed, researchers simply dont know whether BPC-157 consistently delivers the dramatic improvements often claimed online

10.1038/s41401-019-0275-z 40 ZhangX.MaY.LvG.WangH