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doi: 10.1093/nutrit/nuz040 23 HeX.ChenW.SunX.GaoY.HeY.XuX.et al

Nature 575 , 299309 (2019)

Safety profiling of GLP-1MK-801 To evaluate the cardiometabolic safety of the conjugate, key markers of liver damage and cardiovascular health were assessed

It does not simply suppress appetite or create a caloric deficit

If those were ineffective or had limited effect, this can help establish the necessity for the treatment youre recommending

Together with DA, glutamate and aspartate signaling [74] and GABAergic and cholinergic interneurons [75, 76], are expected to modulate striatal function during NPW